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PRLD

Prelude Therapeutics Incorporated

NASDAQ · Healthcare · Biotechnology · US

$5.46
+4.00%
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Next report

Analyst consensus

Next report date
Nov 11, 2026
EPS estimate
-$0.16
Revenue estimate
$35.3M

Latest reported

Last report date
Aug 11, 2026
EPS actual
-$0.14
EPS estimate
-$0.20
Revenue actual
$5.7M
Revenue estimate
$5.7M

Track record

Trailing twelve quarters

EPS beats (12Q)
9
EPS misses (12Q)
2
EPS in line (12Q)
1
Avg surprise (4Q)
-115.1%
Revenue beats (12Q)
0

Analyst ratings

Sell-side consensus

Consensus
Buy
Price target
$8.00
PT range
$8.00 – $8.00
Analysts
2
2 Buy0 Hold0 Sell
Earnings call summaryRead the full call →

Q4 FY2025 · Mar 10, 2026

AI summary of management’s prepared remarks and analyst Q&A · For informational purposes only, not investment advice

Management highlights

Discussed aspects such as the clinical development plan for molecule 396 including a parallel design in myelofibrosis and polycythemia vera with input from key opinion leaders, the rationale behind choosing a degrader approach for CAT6 including selectivity and efficacy advantages, and work on the mutant Cal-R degrader with differentiation points like potency and potential for subcutaneous administration.

Guidance

Cash position was $106 million in cash, which takes the company into the second quarter of 2027, and this does not account for the potential $100 million option payment from Insight.

Segment performance

Not explicitly mentioned in detail

Risks & headwinds

Not discussed in detail

Analyst Q&A

Q: Can you differentiate your molecule from other competitors and why Insight would partner with you?

A: Discussed selectivity profile, learnings from clinic/preclinical stages, and parallel clinical development plan.

Q: Talk about the clinical development plan for molecule 396?

A: Parallel design in myelofibrosis and polycythemia vera, enrolling the right patients and getting FDA approval for the parallel approach.

Q: Talk about the CAT6 degrader?

A: Differentiated by degrader approach for better selectivity and efficacy, plan to file IND by mid - year.

Q: What is the cash position?

A: $106 million in cash, lasting into the second quarter of 2027

Reported results against consensus at the time of each report · Surprise is computed from the estimate on record · Data as of Nov 11, 2026