IOVA

Iovance Biotherapeutics, Inc. (NASDAQ:IOVA) is a clinical-stage biotechnology company founded in 2007 and headquartered in San Carlos, California. Originally incorporated as Lion Biotechnologies, the company changed its name to Iovance Biotherapeutics in June 2017. The company achieved a significant milestone in February 2024 when the FDA approved its lead product <b>Amtagvi</b> (lifileucel), making it the first tumor-infiltrating lymphocyte (TIL) therapy approved for treating solid tumors. This approval transformed Iovance from a purely clinical-stage company into a commercial biotechnology enterprise focused on cancer immunotherapy.