Sionna Therapeutics, Inc. (SION) Insider Trading

Over the last 3 months, SION insiders made 0 open-market buys and 18 sales, a net sale of -$77.6M (SEC Form 4). Over the last 6 months, 81 institutions increased and 49 reduced their position (13F).

Insider Activity

Sentiment
0/100
Buys (3m)
0
Sells (3m)
18
Net (3m)
-$77.6M
Insider trades by month Buys Sells
Dec
Jan
Feb
Mar
Apr
May
Context3-month price +6.2%Institutions accumulating (13F)
DateInsiderTypeSharesPrice
May 29, 2026ORBIMED ADVISORS LLCdirectorSell101$44.49
May 29, 2026Thompson Peter A.directorSell101$44.49
May 11, 2026ORBIMED ADVISORS LLCdirectorSell48,546$44.61
May 11, 2026Thompson Peter A.directorSell184,639$46.22
May 11, 2026Thompson Peter A.directorSell59,767$44.58
May 11, 2026Thompson Peter A.directorSell48,546$44.61
May 11, 2026ORBIMED ADVISORS LLCdirectorSell184,639$46.22
May 11, 2026ORBIMED ADVISORS LLCdirectorSell59,767$44.58
Apr 21, 2026Thompson Peter A.directorSell2,948$44.52
Apr 21, 2026Thompson Peter A.directorSell52,397$44.68
Apr 21, 2026ORBIMED ADVISORS LLCdirectorSell52,397$44.68
Apr 21, 2026ORBIMED ADVISORS LLCdirectorSell2,948$44.52
Apr 16, 2026ORBIMED ADVISORS LLCdirectorSell47,814$44.51
Apr 16, 2026Thompson Peter A.directorSell226,906$45.34
Apr 16, 2026Thompson Peter A.directorSell235,863$44.64
Apr 16, 2026Thompson Peter A.directorSell47,814$44.51
Apr 16, 2026ORBIMED ADVISORS LLCdirectorSell226,906$45.34
Apr 16, 2026ORBIMED ADVISORS LLCdirectorSell235,863$44.64
Mar 6, 2026Fitzpatrick Jenniferofficer: Chief Legal OfficerSell10,250$33.86
Mar 6, 2026Fitzpatrick Jenniferofficer: Chief Legal OfficerOption10,250$6.11
Feb 4, 2026ORBIMED ADVISORS LLCdirectorSell1,890$44.57
Feb 4, 2026Thompson Peter A.directorSell1,890$44.57
Feb 4, 2026Thompson Peter A.directorSell29,063$44.58
Feb 4, 2026ORBIMED ADVISORS LLCdirectorSell29,063$44.58
Jan 26, 2026TPG GP A, LLC10 percent ownerSell250,000$40.00
Jan 6, 2026McKee Charlotteofficer: Chief Medical OfficerGrant155,700$39.21
Jan 6, 2026Beer Caroline Starkofficer: Chief Business OfficerGrant139,340$39.21
Jan 6, 2026Cloonan Michaeldirector, officer: President & CEOGrant436,100$39.21
Jan 6, 2026Ridloff Elenaofficer: CFOGrant165,440$39.21
Jan 6, 2026Fitzpatrick Jenniferofficer: Chief Legal OfficerGrant103,140$39.21

Source: SION SEC Form 4 filings, latest May 29, 2026. For informational purposes only — not investment advice.

Institutional activity (13F)

How institutions changed their SION positions over the last 6 months (SEC Form 13F).

Increased
81
New positions
60
Reduced
49
Sold out
16
Largest moves
InstitutionActionSharesFiled
RA CAPITAL MANAGEMENT, L.P.Reduced9.9MFeb 17, 2026
RA CAPITAL MANAGEMENT, L.P.Unchanged9.9MMay 15, 2026
TPG GP A, LLCUnchanged6.7MFeb 13, 2026
TPG GP A, LLCReduced6.5MMay 15, 2026
ORBIMED ADVISORS LLCReduced3.6MFeb 17, 2026
ORBIMED ADVISORS LLCReduced3.5MMay 15, 2026
VIKING GLOBAL INVESTORS LPUnchanged3.2MMay 15, 2026
VIKING GLOBAL INVESTORS LPUnchanged3.2MFeb 17, 2026
ATLAS VENTURE LIFE SCIENCE ADVISORS, LLCUnchanged3.0MMay 14, 2026
ATLAS VENTURE LIFE SCIENCE ADVISORS, LLCReduced3.0MFeb 13, 2026
ENAVATE SCIENCES GP, LLCUnchanged2.5MFeb 17, 2026
ENAVATE SCIENCES GP, LLCUnchanged2.5MMay 15, 2026
JPMORGAN CHASE & COIncreased1.5MMay 13, 2026
JENNISON ASSOCIATES LLCIncreased1.5MMay 6, 2026
PERCEPTIVE ADVISORS LLCIncreased1.3MMay 29, 2026

Source: SEC Form 13F filings. For informational purposes only — not investment advice.

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