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RCUS

Arcus Biosciences, Inc.

Arcus Biosciences, Inc. Q4 FY2025 earnings call

February 25, 2026 · fiscal period ended 2025-12

EPS · actual vs est

$-0.89 / $-1.11Beat +19.8%

Revenue · actual vs est

$33.0M / $24.9MBeat +32.3%
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Summary

Generated 2026-02-25

Management highlights

Terry Rosen discussed 2026 as transformative year for Arcus, Castatafan's Phase III plans, frontline strategy. Richard reviewed Castatafan ARC-20 data. Jen talked about RCC market opportunity. Juan discussed immunology portfolio progress

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Segment performance

Castatafan shown as best-in-class HIF-2-alpha inhibitor with strong late-line RCC data; immunology portfolio with programs expected in clinic

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Guidance

Expect gap revenue $45 - $55 million in 2026; cash runway to fund operations until at least second half of 2028

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Risks

Risks and uncertainties where actual results may differ from forward-looking statements as described in SEC filings

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Q&A highlights

Questions and answers include about frontline strategy benchmarks, Volvo plus cast study status, biomarker analyses, LightSpark 011 expectations, frontline combo plans, PRX2 safety, and CAVO data expectations with corresponding responses

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Key numbers

Reported versus consensus

Earnings calendar feed

MetricReportedConsensusDeltaPrior year
EPS$-0.89$-1.11+19.8%
Revenue$33.0M$24.9M+32.3%

Transcript

February 25, 2026

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Prior quarters

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