SEPN
Septerna, Inc.
NASDAQ · USHealthcareBiotechnology
$33.24-0.48%
Price as of Jul 20, 2026
SEPN ownership
Septerna, Inc. ownership & insider activity
Latest available institutional positioning and SEC Form 4 insider transactions, coalesced at the company entity level when listings share coverage.
Insider Activity
Sentiment
0/100
Buys (3m)
0
Sells (3m)
11
Net (3m)
-$1.6M
Insider trades by month Buys Sells
Feb
Mar
Apr
May
Jun
Jul
Context3-month price +24.3%Institutions accumulating (13F)
| Date | Insider | Type | Shares | Price |
|---|---|---|---|---|
| Jul 17, 2026 | Bhatt Elizabethofficer: President and COO | Option | 4,000 | $6.81 |
| Jul 17, 2026 | Bhatt Elizabethofficer: President and COO | Sell | 4,000 | $33.99 |
| Jul 2, 2026 | Long Daniel D.officer: SVP, Drug Discovery | Sell | 2,100 | $34.10 |
| Jul 2, 2026 | Long Daniel D.officer: SVP, Drug Discovery | Sell | 1,233 | $34.81 |
| Jul 2, 2026 | Long Daniel D.officer: SVP, Drug Discovery | Option | 3,333 | $2.76 |
| Jun 30, 2026 | Gottesdiener Keith Michaeldirector | Grant | 11,260 | $37.34 |
| Jun 30, 2026 | Tong Jeffrey Kdirector | Grant | 15,000 | $37.34 |
| Jun 30, 2026 | Coulie Bernarddirector | Grant | 15,000 | $37.34 |
| Jun 30, 2026 | Sharp Shalinidirector | Grant | 15,000 | $37.34 |
| Jun 30, 2026 | Bassan Abrahamdirector | Grant | 15,000 | $37.34 |
| Jun 30, 2026 | Shaikhly Samiraofficer: Chief People Officer | Sell | 2,178 | $35.18 |
| Jun 30, 2026 | RA CAPITAL MANAGEMENT, L.P.director, 10 percent owner: | Grant | 15,000 | $37.34 |
| Jun 30, 2026 | Shaikhly Samiraofficer: Chief People Officer | Option | 2,178 | $6.81 |
| Jun 30, 2026 | Simson Jakedirector | Grant | 15,000 | $37.34 |
| Jun 30, 2026 | Ezekowitz Alandirector | Grant | 15,000 | $37.34 |
| Jun 24, 2026 | Long Daniel D.officer: SVP, Drug Discovery | Sell | 8,000 | $35.10 |
| Jun 24, 2026 | Long Daniel D.officer: SVP, Drug Discovery | Sell | 7,000 | $35.97 |
| Jun 24, 2026 | Long Daniel D.officer: SVP, Drug Discovery | Option | 4,471 | $11.70 |
| Jun 24, 2026 | Long Daniel D.officer: SVP, Drug Discovery | Option | 10,529 | $2.76 |
| Jun 16, 2026 | Shaikhly Samiraofficer: Chief People Officer | Option | 6,250 | $11.70 |
| Jun 16, 2026 | Shaikhly Samiraofficer: Chief People Officer | Sell | 6,250 | $35.08 |
| Jun 3, 2026 | Shaikhly Samiraofficer: Chief People Officer | Sell | 1,346 | $28.79 |
| Jun 3, 2026 | Shaikhly Samiraofficer: Chief People Officer | Sell | 1,700 | $27.78 |
| Jun 3, 2026 | Shaikhly Samiraofficer: Chief People Officer | Option | 637 | $2.76 |
| Jun 3, 2026 | Shaikhly Samiraofficer: Chief People Officer | Option | 4,355 | $1.55 |
| Jun 3, 2026 | Shaikhly Samiraofficer: Chief People Officer | Option | 943 | $2.76 |
| Jun 3, 2026 | Shaikhly Samiraofficer: Chief People Officer | Sell | 2,889 | $29.66 |
| May 28, 2026 | Shaikhly Samiraofficer: Chief People Officer | Sell | 11,798 | $30.06 |
| May 28, 2026 | Shaikhly Samiraofficer: Chief People Officer | Option | 11,798 | $6.81 |
| Apr 17, 2026 | Bhatt Elizabethofficer: President and COO | Sell | 1,101 | $25.24 |
Source: SEPN SEC Form 4 filings, latest Jul 17, 2026. For informational purposes only — not investment advice.
Institutional activity (13F)
How institutions changed their SEPN positions over the last 6 months (SEC Form 13F).
Increased
78
New positions
65
Reduced
65
Sold out
34
Largest moves
| Institution | Action | Shares | Filed |
|---|---|---|---|
| RA CAPITAL MANAGEMENT, L.P. | Unchanged | 7.0M | Feb 17, 2026 |
| RA CAPITAL MANAGEMENT, L.P. | Unchanged | 7.0M | May 15, 2026 |
| TRV GP V, LLC | Unchanged | 6.2M | Feb 13, 2026 |
| TRV GP V, LLC | Unchanged | 6.2M | May 7, 2026 |
| DRIEHAUS CAPITAL MANAGEMENT LLC | Reduced | 4.8M | Feb 17, 2026 |
| DRIEHAUS CAPITAL MANAGEMENT LLC | Reduced | 4.4M | May 15, 2026 |
| TRV GP VI, LLC | Unchanged | 4.2M | Feb 13, 2026 |
| TRV GP VI, LLC | Unchanged | 4.2M | May 7, 2026 |
| SAMSARA BIOCAPITAL, LLC | Unchanged | 3.1M | May 15, 2026 |
| SAMSARA BIOCAPITAL, LLC | Unchanged | 3.1M | Feb 17, 2026 |
| GOLDMAN SACHS GROUP INC | Reduced | 2.9M | May 15, 2026 |
| GOLDMAN SACHS GROUP INC | Increased | 2.7M | Mar 25, 2026 |
| SIREN, L.L.C. | Unchanged | 2.0M | May 14, 2026 |
| SIREN, L.L.C. | Reduced | 2.0M | Feb 13, 2026 |
| BLACKROCK, INC. | Increased | 1.8M | May 13, 2026 |
Source: SEC Form 13F filings. For informational purposes only — not investment advice.