OBIO
Orchestra BioMed Holdings, Inc.
NASDAQ · USHealthcareBiotechnology
$3.66-0.54%
Price as of Jul 20, 2026
OBIO ownership
Orchestra BioMed Holdings, Inc. ownership & insider activity
Latest available institutional positioning and SEC Form 4 insider transactions, coalesced at the company entity level when listings share coverage.
Insider Activity
Sentiment
56/100
Buys (3m)
5
Sells (3m)
3
Net (3m)
$35.8K
Insiders buyingCluster buying
Insider trades by month Buys Sells
Nov
Mar
Apr
May
Jun
Jul
Context3-month price -15.4%Institutions accumulating (13F)
| Date | Insider | Type | Shares | Price |
|---|---|---|---|---|
| Jul 2, 2026 | Sherman Darrendirector, officer: See Remarks | Sell | 15,000 | $4.27 |
| Jun 25, 2026 | Connealy Pamela Anndirector | Grant | 21,277 | $4.04 |
| Jun 25, 2026 | Connealy Pamela Anndirector | Grant | 17,327 | — |
| Jun 25, 2026 | Cleary Chrisdirector | Grant | 42,553 | $4.04 |
| Jun 25, 2026 | Aryeh Jasondirector | Grant | 42,553 | $4.04 |
| Jun 25, 2026 | Fain Eric Sdirector | Grant | 17,327 | — |
| Jun 25, 2026 | Fain Eric Sdirector | Tax | 4,261 | — |
| Jun 25, 2026 | Fain Eric Sdirector | Grant | 21,277 | $4.04 |
| Jun 25, 2026 | Pacitti Daviddirector | Grant | 17,327 | — |
| Jun 25, 2026 | Pacitti Daviddirector | Tax | 3,784 | — |
| Jun 25, 2026 | Pacitti Daviddirector | Grant | 21,277 | $4.04 |
| Jun 25, 2026 | Cleary Chrisdirector | Tax | 3,510 | — |
| Jun 25, 2026 | Mack John Prosperdirector | Tax | 3,510 | — |
| Jun 25, 2026 | Mack John Prosperdirector | Grant | 34,653 | — |
| Jun 12, 2026 | Hochman David Pdirector, officer: See Remarks | Tax | 3,283 | $4.02 |
| Jun 12, 2026 | Taylor Andrew Lawrenceofficer: Chief Financial Officer | Tax | 36,352 | $4.02 |
| Jun 2, 2026 | Sherman Darrendirector, officer: See Remarks | Sell | 15,000 | $3.87 |
| Jun 2, 2026 | Hochman David Pdirector, officer: See Remarks | Buy | 5,000 | $3.83 |
| May 29, 2026 | Taylor Andrew Lawrenceofficer: Chief Financial Officer | Tax | 3,076 | $3.98 |
| May 29, 2026 | Sherman Darrendirector, officer: See Remarks | Tax | 4,925 | $3.98 |
| May 20, 2026 | Aryeh Jasondirector | Buy | 665 | $3.75 |
| May 19, 2026 | Aryeh Jasondirector | Buy | 8,971 | $3.90 |
| May 19, 2026 | Hochman David Pdirector, officer: See Remarks | Buy | 5,000 | $3.77 |
| May 18, 2026 | Fain Eric Sdirector | Buy | 20,000 | $4.13 |
| Apr 29, 2026 | RTW INVESTMENTS, LP10 percent owner | Sell | 32 | $4.13 |
| Mar 27, 2026 | Sherman Darrendirector, officer: See Remarks | Tax | 33,317 | $4.57 |
| Mar 27, 2026 | Aiello Joshuaofficer: Principal Accounting Officer | Tax | 241 | $4.57 |
| Mar 27, 2026 | Hochman David Pdirector, officer: See Remarks | Tax | 32,438 | $4.57 |
| Mar 16, 2026 | Hochman David Pdirector, officer: See Remarks | Buy | 10,000 | $4.29 |
| Feb 13, 2026 | Hochman David Pdirector, officer: See Remarks | Grant | 504,000 | — |
Source: OBIO SEC Form 4 filings, latest Jul 2, 2026. For informational purposes only — not investment advice.
Institutional activity (13F)
How institutions changed their OBIO positions over the last 6 months (SEC Form 13F).
Increased
44
New positions
36
Reduced
30
Sold out
22
Largest moves
| Institution | Action | Shares | Filed |
|---|---|---|---|
| RTW INVESTMENTS, LP | Unchanged | 8.3M | May 15, 2026 |
| RTW INVESTMENTS, LP | Unchanged | 8.3M | Feb 17, 2026 |
| PERCEPTIVE ADVISORS LLC | Reduced | 5.1M | Feb 17, 2026 |
| PERCEPTIVE ADVISORS LLC | Reduced | 5.0M | May 29, 2026 |
| VANGUARD CAPITAL MANAGEMENT LLC | New Position | 2.2M | May 15, 2026 |
| VANGUARD GROUP INC | Increased | 1.6M | Jan 29, 2026 |
| ALYESKA INVESTMENT GROUP, L.P. | Reduced | 1.0M | Feb 13, 2026 |
| ALYESKA INVESTMENT GROUP, L.P. | Unchanged | 1.0M | May 15, 2026 |
| PROPEL BIO MANAGEMENT, LLC | New Position | 897K | May 14, 2026 |
| MILLENNIUM MANAGEMENT LLC | Increased | 703K | May 15, 2026 |
| BLACKROCK, INC. | Increased | 636K | May 13, 2026 |
| BLACKROCK, INC. | Reduced | 631K | Feb 12, 2026 |
| AFFINITY ASSET ADVISORS, LLC | Reduced | 573K | Feb 13, 2026 |
| GEODE CAPITAL MANAGEMENT, LLC | Increased | 485K | May 15, 2026 |
| GEODE CAPITAL MANAGEMENT, LLC | Increased | 473K | Feb 9, 2026 |
Source: SEC Form 13F filings. For informational purposes only — not investment advice.