Orchestra BioMed Holdings, Inc. (OBIO) Insider Trading

Over the last 3 months, OBIO insiders made 6 open-market buys and 2 sales, a net purchase of $143K (SEC Form 4). Multiple insiders bought within days of each other (cluster buying). Over the last 6 months, 47 institutions increased and 28 reduced their position (13F).

Insider Activity

Sentiment
78/100
Buys (3m)
6
Sells (3m)
2
Net (3m)
$142.8K
Insiders buyingCluster buying
Insider trades by month Buys Sells
Sep
Nov
Mar
Apr
May
Jun
Context3-month price -15.4%Institutions accumulating (13F)
DateInsiderTypeSharesPrice
Jun 2, 2026Sherman Darrendirector, officer: See RemarksSell15,000$3.87
Jun 2, 2026Hochman David Pdirector, officer: See RemarksBuy5,000$3.83
May 29, 2026Sherman Darrendirector, officer: See RemarksTax4,925$3.98
May 29, 2026Taylor Andrew Lawrenceofficer: Chief Financial OfficerTax3,076$3.98
May 20, 2026Aryeh JasondirectorBuy665$3.75
May 19, 2026Hochman David Pdirector, officer: See RemarksBuy5,000$3.77
May 19, 2026Aryeh JasondirectorBuy8,971$3.90
May 18, 2026Fain Eric SdirectorBuy20,000$4.13
Apr 29, 2026RTW INVESTMENTS, LP10 percent ownerSell32$4.13
Mar 27, 2026Sherman Darrendirector, officer: See RemarksTax33,317$4.57
Mar 27, 2026Aiello Joshuaofficer: Principal Accounting OfficerTax241$4.57
Mar 27, 2026Hochman David Pdirector, officer: See RemarksTax32,438$4.57
Mar 16, 2026Hochman David Pdirector, officer: See RemarksBuy10,000$4.29
Feb 13, 2026Aiello Joshuaofficer: Principal Accounting OfficerGrant70,000$3.82
Feb 13, 2026Sherman Darrendirector, officer: See RemarksGrant397,000
Feb 13, 2026Hochman David Pdirector, officer: See RemarksGrant504,000
Feb 13, 2026Taylor Andrew Lawrenceofficer: Chief Financial OfficerGrant181,000
Feb 6, 2026Cleary ChrisdirectorTax676$3.71
Feb 6, 2026Sherman Darrendirector, officer: See RemarksGrant34,974$2.85
Jan 2, 2026Sherman Darrendirector, officer: See RemarksTax5,588$4.31
Jan 2, 2026Aiello Joshuaofficer: Principal Accounting OfficerTax241$4.31
Jan 2, 2026Taylor Andrew Lawrenceofficer: Chief Financial OfficerTax3,452$4.31
Dec 12, 2025Hochman David Pdirector, officer: See RemarksTax40,355$4.67
Dec 12, 2025Hochman David Pdirector, officer: See RemarksTax3,283$4.67
Dec 12, 2025Taylor Andrew Lawrenceofficer: Chief Financial OfficerTax8,670$4.67
Nov 26, 2025Taylor Andrew Lawrenceofficer: Chief Financial OfficerTax3,071$5.35
Nov 26, 2025Sherman Darrendirector, officer: See RemarksTax40,340$5.35
Nov 17, 2025Hochman David Pdirector, officer: See RemarksBuy5,000$4.07
Nov 14, 2025Hochman David Pdirector, officer: See RemarksTax3,283$4.18
Sep 19, 2025Hochman David Pdirector, officer: See RemarksTax3,283$2.46

Source: OBIO SEC Form 4 filings, latest Jun 2, 2026. For informational purposes only — not investment advice.

Institutional activity (13F)

How institutions changed their OBIO positions over the last 6 months (SEC Form 13F).

Increased
47
New positions
36
Reduced
28
Sold out
19
Largest moves
InstitutionActionSharesFiled
PERCEPTIVE ADVISORS LLCIncreased10.1MMay 29, 2026
RTW INVESTMENTS, LPUnchanged8.3MFeb 17, 2026
RTW INVESTMENTS, LPUnchanged8.3MMay 15, 2026
PERCEPTIVE ADVISORS LLCReduced5.1MFeb 17, 2026
VANGUARD CAPITAL MANAGEMENT LLCNew Position2.2MMay 15, 2026
VANGUARD GROUP INCIncreased1.6MJan 29, 2026
ALYESKA INVESTMENT GROUP, L.P.Reduced1.0MFeb 13, 2026
ALYESKA INVESTMENT GROUP, L.P.Unchanged1.0MMay 15, 2026
PROPEL BIO MANAGEMENT, LLCNew Position897KMay 14, 2026
MILLENNIUM MANAGEMENT LLCIncreased703KMay 15, 2026
BLACKROCK, INC.Increased636KMay 13, 2026
BLACKROCK, INC.Reduced631KFeb 12, 2026
AFFINITY ASSET ADVISORS, LLCReduced573KFeb 13, 2026
GEODE CAPITAL MANAGEMENT, LLCIncreased485KMay 15, 2026
GEODE CAPITAL MANAGEMENT, LLCIncreased473KFeb 9, 2026

Source: SEC Form 13F filings. For informational purposes only — not investment advice.