KPTI
Karyopharm Therapeutics Inc.
NASDAQ · USHealthcareBiotechnology
$8.08-15.04%
Price as of Jul 20, 2026
KPTI ownership
Karyopharm Therapeutics Inc. ownership & insider activity
Latest available institutional positioning and SEC Form 4 insider transactions, coalesced at the company entity level when listings share coverage.
Insider Activity
Sentiment
0/100
Buys (3m)
0
Sells (3m)
7
Net (3m)
-$38.8K
Insider trades by month Buys Sells
Sep
Oct
Jan
Feb
Apr
May
Context3-month price +18.9%Institutions accumulating (13F)
| Date | Insider | Type | Shares | Price |
|---|---|---|---|---|
| May 26, 2026 | Su Zhendirector | Grant | 15,508 | — |
| May 26, 2026 | BOHLIN GAREN Gdirector | Grant | 15,508 | — |
| May 26, 2026 | Schor Chendirector | Grant | 15,508 | — |
| May 26, 2026 | Greene Barry Edirector | Grant | 15,508 | — |
| May 26, 2026 | PAKIANATHAN DEEPIKAdirector | Grant | 15,508 | — |
| May 26, 2026 | Oliger Christy J.director | Grant | 15,508 | — |
| May 15, 2026 | Mano Michaelofficer: EVP, CLO&Secretary | Grant | 700 | — |
| May 15, 2026 | Abate Kristinofficer: Chief Accounting Officer | Sell | 53 | $9.50 |
| May 15, 2026 | Rangwala Reshmaofficer: EVP & Chief Medical Officer | Sell | 408 | $9.50 |
| May 15, 2026 | Abate Kristinofficer: Chief Accounting Officer | Grant | 121 | — |
| May 15, 2026 | Rangwala Reshmaofficer: EVP & Chief Medical Officer | Grant | 947 | — |
| May 15, 2026 | Poulton Stuartofficer: EVP, Chief Development Officer | Sell | 403 | $9.50 |
| May 15, 2026 | Poulton Stuartofficer: EVP, Chief Development Officer | Grant | 896 | — |
| May 15, 2026 | Cheng Sohanya Roshanofficer: EVP & Chief Commercial Officer | Grant | 947 | — |
| May 15, 2026 | Mano Michaelofficer: EVP, CLO&Secretary | Sell | 266 | $9.50 |
| May 15, 2026 | Paulson Richard A.director, officer: President and CEO | Grant | 4,920 | — |
| May 15, 2026 | Cheng Sohanya Roshanofficer: EVP & Chief Commercial Officer | Sell | 324 | $9.50 |
| May 15, 2026 | Paulson Richard A.director, officer: President and CEO | Sell | 2,203 | $9.50 |
| Apr 22, 2026 | Rangwala Reshmaofficer: EVP & Chief Medical Officer | Sell | 449 | $8.94 |
| Feb 19, 2026 | Poulton Stuartofficer: EVP, Chief Development Officer | Sell | 378 | $8.63 |
| Feb 9, 2026 | Paulson Richard A.director, officer: President and CEO | Grant | 81,060 | — |
| Feb 4, 2026 | Macomber Loriofficer: EVP, CFO & Treasurer | Sell | 1,626 | $6.30 |
| Feb 3, 2026 | Mano Michaelofficer: EVP, CLO&Secretary | Grant | 32,415 | — |
| Feb 3, 2026 | Macomber Loriofficer: EVP, CFO & Treasurer | Grant | 32,415 | — |
| Feb 3, 2026 | Cheng Sohanya Roshanofficer: EVP & Chief Commercial Officer | Grant | 32,415 | — |
| Feb 3, 2026 | Poulton Stuartofficer: EVP, Chief Development Officer | Grant | 32,415 | — |
| Feb 3, 2026 | Rangwala Reshmaofficer: EVP & Chief Medical Officer | Grant | 32,415 | — |
| Jan 29, 2026 | Abate Kristinofficer: Chief Accounting Officer | Sell | 50 | $7.03 |
| Jan 29, 2026 | Abate Kristinofficer: Chief Accounting Officer | Grant | 92 | — |
| Jan 22, 2026 | Abate Kristinofficer: Chief Accounting Officer | Sell | 265 | $5.96 |
Source: KPTI SEC Form 4 filings, latest May 26, 2026. For informational purposes only — not investment advice.
Institutional activity (13F)
How institutions changed their KPTI positions over the last 6 months (SEC Form 13F).
Increased
53
New positions
56
Reduced
17
Sold out
24
Largest moves
| Institution | Action | Shares | Filed |
|---|---|---|---|
| IKARIAN CAPITAL, LLC | Increased | 2.6M | May 15, 2026 |
| COMMODORE CAPITAL LP | New Position | 1.9M | May 15, 2026 |
| RA CAPITAL MANAGEMENT, L.P. | New Position | 1.9M | May 15, 2026 |
| ADAGE CAPITAL PARTNERS GP, L.L.C. | Increased | 1.8M | May 15, 2026 |
| T. ROWE PRICE INVESTMENT MANAGEMENT, INC. | Reduced | 1.5M | May 15, 2026 |
| T. ROWE PRICE INVESTMENT MANAGEMENT, INC. | Increased | 1.5M | Feb 19, 2026 |
| SUSQUEHANNA INTERNATIONAL GROUP, LLP | Increased | 1.3M | May 15, 2026 |
| CAPTION MANAGEMENT, LLC | New Position | 1.2M | May 15, 2026 |
| GOLDMAN SACHS GROUP INC | New Position | 948K | May 15, 2026 |
| OPALEYE MANAGEMENT INC. | New Position | 930K | Feb 17, 2026 |
| CATALIO CAPITAL MANAGEMENT, LP | Increased | 898K | May 15, 2026 |
| AFFINITY ASSET ADVISORS, LLC | New Position | 890K | Feb 13, 2026 |
| BOOTHBAY FUND MANAGEMENT, LLC | Increased | 750K | May 15, 2026 |
| Squadron Capital Management LLC | New Position | 750K | May 15, 2026 |
| VANGUARD CAPITAL MANAGEMENT LLC | New Position | 740K | May 15, 2026 |
Source: SEC Form 13F filings. For informational purposes only — not investment advice.