Denali Therapeutics Inc. (DNLI) Insider Trading

Over the last 3 months, DNLI insiders made 0 open-market buys and 1 sale, a net sale of -$72K (SEC Form 4). Over the last 6 months, 230 institutions increased and 128 reduced their position (13F).

Insider Activity

Sentiment
0/100
Buys (3m)
0
Sells (3m)
1
Net (3m)
-$71.6K
Insider trades by month Buys Sells
Jan
Jul
Aug
Dec
Jan
Aug
Context3-month price +22.7%Institutions accumulating (13F)
DateInsiderTypeSharesPrice
Aug 13, 2026Schuth Alexander O.officer: COFO and SecretarySell2,857$25.07
Jun 5, 2026Van Hauwermeiren TimothydirectorGrant6,408
Jun 5, 2026Krognes Steve E.directorGrant6,408
Jun 5, 2026Thornberry NancydirectorGrant6,408
Jun 5, 2026Cook Jennifer E.directorGrant6,408
Jun 5, 2026Klein Peter SdirectorGrant19,226$19.66
Jun 5, 2026BAKER BROS. ADVISORS LPdirectorGrant19,226$19.66
Jun 5, 2026Klein Peter SdirectorGrant6,408
Jun 5, 2026FLATLEY JAY TdirectorGrant19,226$19.66
Jun 5, 2026Thornberry NancydirectorGrant19,226$19.66
Jun 5, 2026BAKER BROS. ADVISORS LPdirectorGrant6,408
Jun 5, 2026Schenkein David PdirectorGrant19,226$19.66
Jun 5, 2026Cook Jennifer E.directorGrant19,226$19.66
Jun 5, 2026FLATLEY JAY TdirectorGrant6,408
Jun 5, 2026Krognes Steve E.directorGrant19,226$19.66
Jun 5, 2026Schenkein David PdirectorGrant6,408
Jun 5, 2026Van Hauwermeiren TimothydirectorGrant19,226$19.66
Jan 8, 2026Watts Ryan J.director, officer: President and CEOSell35,198$16.50
Jan 8, 2026Schuth Alexander O.officer: COFO and SecretarySell17,218$16.50
Jan 5, 2026Watts Ryan J.director, officer: President and CEOGrant236,880$16.27
Jan 5, 2026Schuth Alexander O.officer: COFO and SecretaryGrant57,700
Jan 5, 2026Watts Ryan J.director, officer: President and CEOGrant78,960
Jan 5, 2026Schuth Alexander O.officer: COFO and SecretaryGrant173,100$16.27
Dec 15, 2025BAKER BROS. ADVISORS LPdirectorBuy2,095,191$0.01
Dec 15, 2025BAKER BROS. ADVISORS LPdirectorBuy190,523$0.01
Nov 6, 2025Van Hauwermeiren TimothydirectorGrant10,632
Nov 6, 2025Van Hauwermeiren TimothydirectorGrant31,897$14.92
Aug 14, 2025Ho Caroleofficer: Chief Medical OfficerSell2,937$13.58
Aug 14, 2025Schuth Alexander O.officer: COFO and SecretarySell2,937$13.58
Aug 14, 2025Ho Caroleofficer: Chief Medical OfficerSell806$14.64

Source: DNLI SEC Form 4 filings, latest Aug 13, 2026. For informational purposes only — not investment advice.

Institutional activity (13F)

How institutions changed their DNLI positions over the last 6 months (SEC Form 13F).

Increased
230
New positions
110
Reduced
128
Sold out
30
Largest moves
InstitutionActionSharesFiled
T. Rowe Price Investment Management, Inc.Increased16.2MAug 14, 2026
BlackRock, Inc.Increased14.0MAug 7, 2026
BLACKROCK, INC.Increased13.0MMay 13, 2026
BAILLIE GIFFORD & COReduced12.1MMay 8, 2026
BAILLIE GIFFORD & COReduced12.0MAug 6, 2026
T. ROWE PRICE INVESTMENT MANAGEMENT, INC.Increased8.5MMay 15, 2026
STATE STREET CORPIncreased7.0MAug 7, 2026
TEMASEK HOLDINGS (PRIVATE) LTDUnchanged7.0MMay 12, 2026
Temasek Holdings (Private) LtdUnchanged7.0MAug 7, 2026
VANGUARD PORTFOLIO MANAGEMENT LLCIncreased6.5MAug 13, 2026
VANGUARD CAPITAL MANAGEMENT LLCIncreased6.3MAug 13, 2026
STATE STREET CORPIncreased6.3MMay 15, 2026
VANGUARD CAPITAL MANAGEMENT LLCNew Position6.1MMay 15, 2026
VANGUARD PORTFOLIO MANAGEMENT LLCNew Position6.1MMay 8, 2026
FMR LLCReduced4.6MMay 15, 2026

Source: SEC Form 13F filings. For informational purposes only — not investment advice.