Amylyx Pharmaceuticals, Inc. (AMLX) Insider Trading
Over the last 3 months, AMLX insiders made 1 open-market buy and 0 sales, a net purchase of $51K (SEC Form 4). Over the last 6 months, 147 institutions increased and 100 reduced their position (13F).
Insider Activity
Sentiment
100/100
Buys (3m)
1
Sells (3m)
0
Net (3m)
$51.3K
Insiders buyingFirst buy in 2 quarters
Insider trades by month Buys Sells
Oct
Dec
Jan
Feb
Mar
May
Context3-month price +1.5%Institutions accumulating (13F)
| Date | Insider | Type | Shares | Price |
|---|---|---|---|---|
| May 26, 2026 | Firestone Karendirector | Buy | 3,800 | $13.51 |
| Mar 9, 2026 | Cohen Joshua Bdirector, officer: Co-Chief Executive Officer | Grant | 248,865 | — |
| Mar 9, 2026 | Bedrosian Camille Lofficer: Chief Medical Officer | Grant | 143,985 | $14.10 |
| Mar 9, 2026 | Bedrosian Camille Lofficer: Chief Medical Officer | Grant | 95,990 | — |
| Mar 9, 2026 | Klee Justin B.director, officer: Co-Chief Executive Officer | Grant | 373,295 | $14.10 |
| Mar 9, 2026 | Klee Justin B.director, officer: Co-Chief Executive Officer | Grant | 248,865 | — |
| Mar 9, 2026 | FRATES JAMES Mofficer: Chief Financial Officer | Grant | 143,985 | $14.10 |
| Mar 9, 2026 | FRATES JAMES Mofficer: Chief Financial Officer | Grant | 95,990 | — |
| Mar 9, 2026 | Mazzariello Ginaofficer: Chief Legal Officer | Grant | 111,990 | $14.10 |
| Mar 9, 2026 | Mazzariello Ginaofficer: Chief Legal Officer | Grant | 74,660 | — |
| Mar 9, 2026 | Cohen Joshua Bdirector, officer: Co-Chief Executive Officer | Grant | 373,295 | $14.10 |
| Mar 4, 2026 | Mazzariello Ginaofficer: Chief Legal Officer | Sell | 6,844 | $14.52 |
| Mar 4, 2026 | Bedrosian Camille Lofficer: Chief Medical Officer | Sell | 6,461 | $14.58 |
| Mar 4, 2026 | Klee Justin B.director, officer: Co-Chief Executive Officer | Sell | 29,282 | $14.47 |
| Mar 4, 2026 | Cohen Joshua Bdirector, officer: Co-Chief Executive Officer | Sell | 29,282 | $14.48 |
| Mar 4, 2026 | FRATES JAMES Mofficer: Chief Financial Officer | Sell | 7,909 | $14.52 |
| Feb 25, 2026 | Mazzariello Ginaofficer: Chief Legal Officer | Sell | 3,419 | $14.14 |
| Feb 4, 2026 | Mazzariello Ginaofficer: Chief Legal Officer | Sell | 3,448 | $14.65 |
| Feb 4, 2026 | Cohen Joshua Bdirector, officer: Co-Chief Executive Officer | Sell | 15,500 | $14.68 |
| Feb 4, 2026 | Klee Justin B.director, officer: Co-Chief Executive Officer | Sell | 15,500 | $14.69 |
| Feb 4, 2026 | FRATES JAMES Mofficer: Chief Financial Officer | Sell | 3,557 | $14.65 |
| Jan 20, 2026 | Klee Justin B.director, officer: Co-Chief Executive Officer | Sell | 1,995 | $13.89 |
| Jan 20, 2026 | Cohen Joshua Bdirector, officer: Co-Chief Executive Officer | Option | 2,818 | $7.57 |
| Jan 20, 2026 | Cohen Joshua Bdirector, officer: Co-Chief Executive Officer | Sell | 1,974 | $13.83 |
| Jan 20, 2026 | Cohen Joshua Bdirector, officer: Co-Chief Executive Officer | Sell | 136,193 | $13.59 |
| Jan 20, 2026 | Klee Justin B.director, officer: Co-Chief Executive Officer | Option | 197,153 | $7.57 |
| Jan 20, 2026 | Klee Justin B.director, officer: Co-Chief Executive Officer | Option | 2,847 | $7.57 |
| Jan 20, 2026 | Klee Justin B.director, officer: Co-Chief Executive Officer | Sell | 136,193 | $13.58 |
| Jan 20, 2026 | Cohen Joshua Bdirector, officer: Co-Chief Executive Officer | Option | 197,182 | $7.57 |
| Jan 8, 2026 | FRATES JAMES Mofficer: Chief Financial Officer | Sell | 3,326 | $11.11 |
Source: AMLX SEC Form 4 filings, latest May 26, 2026. For informational purposes only — not investment advice.
Institutional activity (13F)
How institutions changed their AMLX positions over the last 6 months (SEC Form 13F).
Increased
147
New positions
62
Reduced
100
Sold out
62
Largest moves
| Institution | Action | Shares | Filed |
|---|---|---|---|
| FMR LLC | Increased | 16.6M | May 15, 2026 |
| PERCEPTIVE ADVISORS LLC | Increased | 16.6M | May 29, 2026 |
| FMR LLC | Increased | 16.5M | Feb 17, 2026 |
| BLACKROCK, INC. | Increased | 9.1M | Feb 12, 2026 |
| BLACKROCK, INC. | Reduced | 8.8M | May 13, 2026 |
| PERCEPTIVE ADVISORS LLC | Reduced | 8.3M | Feb 17, 2026 |
| TCG CROSSOVER MANAGEMENT, LLC | Unchanged | 6.2M | Feb 17, 2026 |
| TCG CROSSOVER MANAGEMENT, LLC | Unchanged | 6.2M | May 15, 2026 |
| VANGUARD GROUP INC | Increased | 5.8M | Jan 29, 2026 |
| COMMODORE CAPITAL LP | Unchanged | 5.7M | May 15, 2026 |
| COMMODORE CAPITAL LP | Increased | 5.7M | Feb 17, 2026 |
| JANUS HENDERSON GROUP PLC | Increased | 5.0M | May 18, 2026 |
| SATURN V CAPITAL MANAGEMENT LLC | Reduced | 4.5M | Feb 17, 2026 |
| JANUS HENDERSON GROUP PLC | Increased | 4.5M | Feb 17, 2026 |
| SATURN V CAPITAL MANAGEMENT LLC | Reduced | 4.3M | May 15, 2026 |
Source: SEC Form 13F filings. For informational purposes only — not investment advice.